Overview
Cryo-EM Facility Manager – Strand, London, WC2R 2LS
About us
King’s College London is seeking a highly motivated cryo-electron microscopy (cryo-EM) expert to manage its newly established Cryo-EM Structural Discovery Facility. This is an exciting opportunity to contribute to cutting-edge structural biology research through single-particle cryo-electron microscopy and cryo-electron tomography, while playing a pivotal role in development the operation of the facility.
At the heart of this facility is a 200 keV JEOL cryoARM200 electron microscope with an energy filter and a top-of-the-range Gatan K3 direct electron detector. This instrument can produce reconstructions at better than 3 Å resolution and acts as a “feeder” instrument for the LonCEM Titan Krios microscope at the Francis Crick Institute, where King’s has a share. The facility also includes a Leica GP2 automated vitrification system for sample preparation.
The facility is part of our Research Infrastructure team within the Research Management and Innovation Directorate (RMID) and works closely with the Centre for Ultrastructural Imaging (CUI). Together, we provide everything from cryo-EM sample preparation and storage to screening and high-resolution data collection.
About the role
As Facility Manager, you’ll lead the operation and development of the Cryo-EM Structural Discovery Facility, while making a significant intellectual contribution to collaborative research. You’ll support a range of research projects, from experimental design and sample preparation through to data acquisition, analysis and interpretation.
The role includes operating the electron microscope and providing expert guidance to academic and industry researchers, helping to generate high-quality, publishable outputs. The post holder will play a key role in advancing methodological approaches, optimising cryo-EM workflows, and introducing new techniques to enhance research capability.
Working closely with the Academic Director, you will contribute to the ongoing development of the facility’s scientific capabilities, research output and strategic direction.
The appointment requires deep technical expertise in cryo-EM, including sample preparation, instrument operation, automated data acquisition and image processing. Strong leadership and organisational skills are essential to support a dynamic research environment and ensure the facility remains aligned with King’s research priorities.
This is a full-time post (35 Hours per week), and you will be offered an indefinite contract.
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